High-Risk Human Papillomavirus Detection in Oropharyngeal, Nasopharyngeal, and Oral Cavity Cancers
نویسندگان
چکیده
منابع مشابه
High-risk human papillomavirus detection in oropharyngeal, nasopharyngeal, and oral cavity cancers: comparison of multiple methods.
IMPORTANCE Human papillomaviruses are now recognized as an etiologic factor in a growing subset of head and neck cancers and have critical prognostic importance that affects therapeutic decision making. There is no universally accepted gold standard for high-risk HPV (hrHPV) assessment in formalin-fixed, paraffin-embedded (FFPE) tissue specimens, nor is there a clear understanding of the freque...
متن کاملHuman Papillomavirus Infection in Oral Cavity and Oropharyngeal Cancers: Are They the Same Story?
Background: Nowadays, human papillomavirus (HPV) infection becomes the main risk factor for head and neck cancer development. In Thailand, the related role of this viral infection to head and neck cancer is still unknown and not well established. Objective: To identify different characteristics of oral cavity and oropharyngeal cancer, and to determine the HPV-associated prevalence of these two ...
متن کاملHigh-risk human papillomavirus in nasopharyngeal carcinoma.
BACKGROUND Human papillomavirus (HPV), a cause of oropharyngeal carcinoma, has also been implicated as an etiologic agent in nasopharyngeal carcinomas. METHODS We performed p16 immunohistochemistry and in situ hybridization for Epstein-Barr virus (EBV) and HPV on 45 carcinomas of the nasopharynx. RESULTS Thirty-four (76%) carcinomas were EBV-positive/HPV-negative, 7 (16%) were EBV-negative/...
متن کاملRole of high-risk human papillomavirus in the etiology of oral and oropharyngeal cancers in Thailand: A case–control study
Background Among developing countries, Thailand shows no increase in the incidence of human papillomavirus-driven oropharyngeal cancer. The causal role of human papillomavirus infection in this pathology has not been researched thoroughly. Methods A hospital-based, case-control study was performed which included 104 patients with newly diagnosed oral and oropharyngeal squamous cell carcinomas...
متن کاملComparative study between biopsy and brushing sampling methods for detection of human papillomavirus in oral and oropharyngeal cavity lesions.
INTRODUCTION Many epidemiological studies have suggested that human papillomavirus (HPV), especially type 16, is involved in the genesis of squamous cell carcinoma of the oral cavity and oropharynx, especially in young, non-smoking patients; thus, its detection in lesions in this region is important. OBJECTIVE To clarify the capacity of the brushing sampling method to detect the presence of H...
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ژورنال
عنوان ژورنال: JAMA Otolaryngology–Head & Neck Surgery
سال: 2013
ISSN: 2168-6181
DOI: 10.1001/jamaoto.2013.5460